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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanol is a drug intermediate for the synthesis of various active compounds. It is for research use only and not sold to patients.
For research use only
Drug intermediate for various active compounds
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HO-PEG3-(CH2)6-Cl is a hydroxy-terminated PEG3 linker bearing a 6-chlorohexyl group, designed for assembling PROTACs and other bifunctional molecules. It serves as a spacer to connect targeting ligands and E3 ligase binders in targeted protein degradation research and is supplied for research use only.
Hydroxy-terminated PEG3 spacer with a 6-chlorohexyl terminus.
Designed for synthesis of PROTACs and bifunctional conjugates.
Molecular formula C12H25ClO4; molecular weight 268.78 g·mol⁻¹.
CAS number 1355955-95-1 for unambiguous identification.
Reported purity about 95% from suppliers' product listings.
Supplied in small milligram-scale packages for research synthesis.
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Methotrexate hydrate is a substance that affects cell growth and division. It is commonly used to fight certain diseases, especially cancer and autoimmune diseases, by inhibiting the process by which cells synthesize DNA. As a biochemical reagent, it can be utilized as a biological material or organic compound for life science-related research.
Affects cell growth and division
Commonly used in cancer and autoimmune disease research
Inhibits DNA synthesis in cells
Can be used as a biochemical reagent for life science research
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N-(Azido-PEG2)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that functions as a click chemistry reagent. It contains an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. This linker is used in the synthesis of PROTACs, which leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
Used in the synthesis of PROTACs.
Functions as a click chemistry reagent.
Contains an Azide group, enabling CuAAc reactions with Alkyne groups and SPAAC reactions with DBCO or BCN groups.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More